The impact of MG149, a KAT8 inhibitor, on mitophagy: cell-based in vitro assays

Output Details

This protocol describes a set of mitophagy-related cell-based in vitro assays used (ex: TMRM, mitoKeima) to evaluate the functional significance of MG149 and KAT8 inhibition.
Tags
  • Activity Assay
  • Cell biology
  • Cell culture
  • Mitophagy
  • PINK1

Meet the Authors

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    Capucine de Talhouet, MSc

    Key Personnel: Team Hardy

    University College London

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    Benjamin O’Callaghan, PhD

    Key Personnel: Team Hardy

    University College London

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    Noemi Esteras

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    Marc P.M. Soutar

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    Helene Plun-Favreau, PhD

    Collaborating PI: Team Hardy

    University College London