PI3KC3-C1 bound to RAB1A in the inactive state. Consensus refinement

PI3KC3C1 bound to RAB1A, Inactive state, VPS34 kinase domain local refinement

PI3KC3-C1 bound to RAB1A. Consensus inactive state refinement of particle subset with strongest kinase domain density

PI3KC3-C1 bound to RAB1A. Local refinement of VPS34KD in the inactive state, particle subset

PI3KC3-C1 bound to RAB1A. VPS34 kinase domain in the active conformation, consensus reconstruction

PI3KC3-C1 bound to RAB1A, VPS34 in active state.

Cryo-EM reconstruction of PI3KC3-C1 in complex with Human RAB1A(Q70L)

Cryo EM reconstruction of PI3KC3-C1 in complex with Human RAB1A(Q70L), VPS34 kinase domain in the inactive conformation

PI3KC3-C1 in complex with RAB1A. VPS34 kinase domain active conformation