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Calbindin KD Mouse – Experimental Cross

By Katherine Brimblecombe, PhD and Stephanie Cragg, PhD
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Output Details

Description
Calbindin-knockdown (CalbKD) animals were generated by crossing homozygous DAT IRES cre (RRID:IMSR_JAX:006660) mice with homozygous CalbTM2 mice (loxP sites flanking Exon1) donated by Prof. Meyer (University of Munich) (RRID:IMSR_JAX:031936), generating double-heterozygous offspring with decreased calb1 expression in DAT-expressing cells. CalbWT control mice were age- and sex-matched heterozygous DAT IRES cre mice. These experimental and control mice are not routinely maintained as a colony.
Tags
  • Mouse
Team
Team Cragg
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

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Aligning Science Across Parkinson's
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