pSpCas9-2A-PuroTBK1-gRNA (PX459)

Output Details

Description
pSpCas9-2A-PuroTBK1-gRNA (PX459)
Team
Team De Camilli
Program
Collaborative Research Network
Theme
PD Functional Genomics

Related Research

Lysosomal TBK1 responds to amino acid availability to relieve Rab7-dependent mTORC1 inhibition

This study reveals that TBK1 is recruited to lysosomes when amino acids are abundant where it phosphorylates Rab7 and thus relieves Rab7-dependent suppression of mTORC1 signaling from lysosomes.

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Plasmid construction – Chen et al. 2025 NSMB

Standard cloning procedure.

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Image Processing and 3D Reconstruction – Chen et al. 2025 NSMB

Image processing and 3D reconstruction applied in Chen et al. 2025 NSMB

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