Single-cell-RNA-seq-of-the-CRISPR-engineered-endogenous-tauopathy-model

Analysis code supporting the study “Transcriptional programs mediating neuronal toxicity and altered glial–neuronal signaling in a Drosophila knock-in tauopathy model.”  The repository contains scripts and notebooks for Cell Ranger preprocessing, Scrublet doublet detection, Seurat-based single-cell RNA-seq analysis, trajectory analysis, FlyPhoneDB, pySCENIC, OmicsIntegrator, and generation of selected manuscript results.  Associated sequencing data are available from GEO under accession GSE223345.