Catalog

ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.

Protocol

Gene expression analysis by qPCR

Protocol for gene expression analysis by quantitative Real-Time PCR (qPCR).

Article

In vivo reduction of age-dependent neuromelanin accumulation mitigates features of Parkinson’s disease

Preprint: Using a newly developed rodent model, the authors assessed whether the intracellular buildup of neuromelanin that occurs with age can be slowed down in vivo to prevent or attenuate Parkinson’s disease. when neuromelanin reaches a specific threshold, it can trigger PD pathology in this animal model.

Protocol

Determination of free and protein-bound DA and NE and their metabolites and oxidation products by UPLC-MS/MS method

Protocol for the determination of free and protein-bound DA and NE and their metabolites and oxidation products by UPLC-MS/MS method.