Cinder
By onAn open-source web-based indexer for proteomics search output and differential analysis that enable sharing and search of lab generated data.
cookeR
By onAn open-source and low-overhead commandline tool and Golang library for installing and managing portable R installation for headless or server-based usage.
Contort
By onAn open-source alternative web-based user interface for the protein conservation evaluation pipeline ConSurf.
Cauldron Plugin Registry
By onA separate registry open-source self-hostable backend that can be used to provide a centralized resource where Cauldron plugin writers can submit their data analysis pipelines
Datasets and Key Resource Table for Lunn et al., 2026: Elevated phosphorylated α-synuclein and phosphorylated-tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis
By onDataset and key resource table for the study: Elevated phosphorylated α-synuclein and phosphorylated-tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis, by Lunn et al., 2026.
Cauldron
By onAn open-source multiplatform data analysis pipeline runner platform that require no installation.
Key Resource Table for Franz et al., 2025: 3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x-ray phase-contrast tomography
By onThis is the Key Resource File for Franz et al., 2025. The Zenodo entry includes image files, an excel resource file with links to datasets, resources, protocols, and code, as well as additional datasets.
HyDrop Bead Generation & PCR Barcoding V.2
By onProtocol for producing dissolvable barcoded hydrogel beads used in HyDrop experiments.
Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress
By onCryo-ET showed protein aggregates, altered cristae, and reduced ribosome complexes in stressed mitochondria. Mitochondrial Hsp60 undergoes conformational changes to aid in protein folding, shedding light on mitochondrial proteostasis mechanisms.
FISH CODETECTION
By onDIG and Fluorescein labeled riboprobes Fluorescent in situ hybridization Frozen brain sections
Open Field Behavior in Mice-Ding Lab
By onThe open field test is widely used to assess spontaneous locomotor activity, exploratory behavior, and anxiety-like responses in rodents.
Single-cell extracellular recordings (surgery, STN optotagging, LHb recordings)
By onProtocol for single cell extracellular recordings (surgery, STN optotagging, LHb recordings)
Electrophysiological Recordings
By onProtocol for electrophysiological patch clamp/voltage clamp recordings.
Tabular datasets for “A role for the subthalamic nucleus in aversive learning”
By onTabular datasets for "A role for the subthalamic nucleus in aversive learning." Includes FISH, electrophysiological, and behavioral datasets.
Isolation of mouse midbrain, RNA purification, reverse transcription, and quantitative PCR
By onProtocol for dissection of midbrain from mice, followed by isolation of RNA from midbrain samples, reverse transcription of mRNA to cDNA, and quantitative real-time PCR for analysis of VMAT2 expression levels.
Ancestry-specific peripheral immune gene-expression mediates the risk of neurodegenerative disease
By onThis study shows that genes linked to brain diseases like Alzheimer’s and Parkinson’s act through the immune system outside the brain, with effects varying by ancestry. It highlights the need for ancestry-specific genetic studies.
Mechanisms and clinical implications of gut-brain interactions
By onResearch in the past decade has shed light on the gut-brain connection, revealing its role in disease and therapeutics. Targeting gut-brain pathways shows promise for therapeutic benefits.
Regulator of G protein signaling 10: a critical regulator of chronic systemic inflammation in parkinson’s disease
By onThe inflammatory response must be regulated to avoid chronic systemic inflammation. Imbalance can lead to diseases like Parkinson's. The review explores the link between inflammation, Parkinson's, and the role of RGS10 in regulating inflammation.
Expanding Our Research Horizons: 2026 CRN Investigators Meeting
In this blog, Hetal Shah, PhD, senior program officer, and Dana Lewis, PhD, program officer at ASAP and the Coalition for Aligning Science, discuss highlights from the 2026 CRN Annual Investigators Meeting, emphasizing how new research themes and cross-disciplinary collaboration are accelerating progress in Parkinson’s disease research.
