9MHG
By onCryo EM reconstruction of PI3KC3-C1 in complex with Human RAB1A(Q70L), VPS34 kinase domain in the inactive conformation
Data associated with “Structural pathway for PI 3-kinase regulation by VPS15 in autophagy”
By onAll data from the manuscript "Structural pathway for PI 3-kinase regulation by VPS15 in autophagy" All figures can be reproduced from the files in this zenodo upload.
Data upload for Tagless LysoIP method for molecular profiling of lysosomal content in clinical samples
By onSummary: Raw data for the tagless LysoIP manuscript is available.
Supporting data for “PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection”
By onData associated with “PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection”
EMD-40735
By onStructure of human ULK1 complex core (2:2:2 stoichiometry) of the ATG13(450-517) mutant
Mass photometry source data of Figure6
By onMass photometry source data of 'Fig. 6: Concentration-dependent stoichiometry shift of ULK1C' for DOI:2023.06.01.543278
Primary Dataset for article “Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production”
By onPrimary Dataset for article "Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production"
Autophagic stress activates distinct compensatory secretory pathways in neurons data
By onPrimary data, raw images, and full western blots pertaining to "Autophagic stress activates distinct compensatory secretory pathways in neurons data" Palumbos et al., 2025.
Part1: PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinson’s disease
By onData and files for Western blot analysis and ciliation experiments on PPM1M, a potential Parkinson's disease-related phosphatase, are available for publication.
Identification of global proteome changes upon DFP treatment of HeLa cells
By onStudy aimed to find proteins degraded by DFP mimicking hypoxia-induced mitophagy. Identified proteins degraded after 24h DFP treatment, focusing on mitochondrial proteins.
Identification of NIX-GST and BNIP3-GST interactors
By onStudy aimed to find proteins interacting with mitophagy receptors NIX or BNIP3 by incubating NIX-GST or BNIP3-GST with HeLa cell lysate to identify binding partners.
Identification of global proteome changes upon rapalog-induced tethering of WIPI2 to the mitochondrial outer membrane in wild-type or NIX/BNIP3 DKO HeLa cells
By onWe aimed to identify proteins that would be turned over upon artificial tethering of WIPI2 to the mitochondrial surface upon rapalog treatment.
Structure of the human prohibitin complex in the closed state
By onStructure of the human prohibitin complex in the closed state
Structure of the human prohibitin complex in the closed state_EMDB-70179
By onStructure of the human prohibitin complex in the closed state
Structure of the human prohibitin complex in the open state
By onStructure of the human prohibitin complex in the open state
